Cardiomyopathy & Heart Failure
Defining multicellular mechanisms of inherited and acquired cardiomyopathy to identify new therapeutic strategies.
Learn More →Sayed Lab · Stanford University
Engineering Human Cardiovascular Models to Understand Disease and Discover New Therapies
We integrate patient-derived biospecimens, human iPSCs, multicellular cardiovascular models, genome engineering, and single-cell and spatial multi-omics to uncover mechanisms of cardiovascular disease.
Endothelial
Network
Network
Cardiac
Organoid
Organoid
Single-Cell
Multi-omics
Multi-omics
Spatial
Transcriptomics
Transcriptomics
From Patients to Therapies
Patients &
Biobank
Biobank
iPSCs
Cardiovascular
Cells
Cells
Organoids &
Engineered Tissues
Engineered Tissues
Single-Cell & Spatial
Multi-Omics
Multi-Omics
Mechanisms
Therapeutic
Interventions
Interventions
Our Research
Multicellular Approaches. Human Impact.
Vascular Biology & Regeneration
Investigating endothelial function, vascular remodeling, and regeneration in health and disease.
Learn More →
Precision Cardio-Oncology
Uncovering mechanisms of cancer therapy-associated cardiotoxicity and developing precision cardioprotective strategies.
Learn More →
Functional Cardiovascular Genomics
Using genome engineering and multi-omics to discover regulatory pathways that drive cardiovascular disease.
Learn More →
Environmental Cardiovascular Disease
Studying the impact of environmental exposures on the cardiovascular system using human models.
Learn More →